Precision structure

modeling with AI.

Accelerating pharmaceutical breakthroughs by bridging cryo-EM data and atomic resolution with state-of-the-art deep learning.

Proprietary Software Suite

Licensing is available for research partners to retain on-site control of proprietary information and confidential computations.

DeepMainmast

Protein structure modeling from CryoEM

Powered by deep learning and combinatorial optimization, structures can be modeled even from density that is not classically of atomic resolution.

  • Direct modeling from density maps

  • Deep learning backbone detection

  • Combinatorial optimization

CryoREAD

DNA/RNA structure modeling from CryoEM

Specialized deep learning architecture for accurately modeling DNA and RNA structures directly from cryo-EM maps.

  • Nucleotide identification

  • Backbone tracing

  • Complex folding analysis

DAQ-Score

CryoEM Structure validation

Retargets neural network architectures to identify residues that have potentially been incorrectly assigned to a density region.

  • Residue validation

  • Density region analysis

  • Automated error flagging