AI-Powered Biomolecular Structure Solutions

Accelerate structural research and drug discovery with advanced software and expert scientific services for biomolecular structure prediction, modeling, and validation.

Intellicule offers commercial software licenses and a wide range of customized modeling and scientific services. Building on our expertise in cryo-EM and deep learning, we help pharmaceutical, biotechnology, and academic researchers generate accurate, reliable structural models and pursue downstream discovery and development with greater confidence.

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3D rendering of a blue and pink tangled protein structure

Commercial Software Licensing

Flexible licensing options are available for our proprietary software suite, including on-site deployment. Organizations can retain control of confidential data, proprietary research, and sensitive computations within their own secure environments.

Featured Software

Illustration of a protein channel embedded in a cell membrane, with molecules passing through.

DeepMainmast

Protein structure modeling from cryo-EM density map

Powered by deep learning and combinatorial optimization, structures can be modeled even from density that is not classically of atomic resolution.

  • Direct modeling from density maps

  • Deep learning backbone detection

  • Combinatorial optimization

A digital illustration of DNA double helix strands intertwined with a stylized molecular structure, featuring a central glowing blue sphere and surrounding blue, pink, and red molecular particles.

CryoREAD

DNA/RNA structure modeling from cryo-EM

Specialized deep learning architecture for accurately modeling DNA and RNA structures directly from cryo-EM maps.

  • Nucleotide identification

  • Backbone tracing

  • Complex folding analysis

Colorful, abstract 3D rendering of a tangled, ribbon-like structure in shades of blue, purple, pink, and orange on a black background.

DAQ-Score

Cryo-EM Structure validation

Retargets neural network architectures to identify residues that have potentially been incorrectly assigned to a density region.

  • Residue validation

  • Density region analysis

  • Automated error flagging